Differential expression of virulence genes and role of <i>gyrA</i> mutations in quinolone resistant and susceptible strains of <i>Salmonella </i>Weltevreden and Newport isolated from seafood

Abstract

This study provided valuable information on the difference in the growth, cytotoxicity, infectivity and expression of virulence genes in resistant and susceptible strains. Furthermore, the gyrA mutation was shown to be the main mechanism of quinolone resistance in Salmonella other than the overexpression of efflux pumps or the presence of plasmid mediated quinolone resistance genes.