<i>N</i>‐Imide Ylide‐Based Reactions: CH Functionalization, Nucleophilic Addition and Cycloaddition

Abstract

Abstract As valuable building blocks for introducing nitrogen, N ‐imide ylides represent an important class of reactive species and are synthons for the synthesis of nitrogen‐containing heterocycles that potentially have biological activities. During the past decades, tremendous efforts have been devoted to the tandem processes involving N ‐imide ylides as well as their asymmetric applications. In particular, several types of N ‐imide ylide‐based reactions have been established, such as CH functionalization, nucleophilic addition, and cycloaddition, etc. In this review, recent advances in N ‐imide ylides chemistry are presented ordered according to the sequence of various reaction types. magnified image