Hyperlactatemia is an independent predictor of mortality and denotes distinct subtypes of severe sepsis and septic shock

Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

Emanuel P. Rivers, Bryant Nguyen, Suzanne Havstad et al. · New England Journal of Medicine · 2001 · 10.7K citations · Full text

Surviving Sepsis Campaign

R. Phillip Dellinger, Mitchell M. Levy, Andrew Rhodes et al. · Critical Care Medicine · 2013 · 9.7K citations

Critical Care Management, Critical Care Medicine, Severe Sepsis +13

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

R.P. Dellinger, Mitchell M. Levy, Andrew Rhodes et al. · Intensive Care Medicine · 2013 · 7.3K citations · Full text

Trauma Resuscitation, Critical Care Management, Severe Sepsis +10

Effect of Treatment With Low Doses of Hydrocortisone and Fludrocortisone on Mortality in Patients With Septic Shock

Djillali Annane · JAMA · 2002 · 3.1K citations

Hydrocortisone Therapy for Patients with Septic Shock

Charles L. Sprung, Djillali Annane, Didier Keh et al. · New England Journal of Medicine · 2008 · 2.1K citations · Full text