Synthesis of Enantiopure 3-Azabicyclo[3.3.0]octen-7-one Derivatives via Intramolecular Pauson−Khand Cycloaddition Reaction Using Tri<i>-O</i>-acetyl-<scp>d</scp>-glucal as Starting Material

Abstract

Some N-substituted-3-azabicyclo[3.3.0]octen-7-one derivatives have been synthesized in an enantiomerically pure form starting from tri-O-acetyl-D-glucal via intramolecular Pauson-Khand (IPK) cycloaddition.