Spermidinium <i>closo</i>-dodecaborate-encapsulating liposomes as efficient boron delivery vehicles for neutron capture therapy

Abstract

closo-Dodecaborate-encapsulating liposomes were developed as boron delivery vehicles for neutron capture therapy. The use of spermidinium as a counter cation of closo-dodecaborates was essential not only for the preparation of high boron content liposome solutions but also for efficient boron delivery to tumors.