Association of folate receptor (<i>folr1</i>, <i>folr2</i>, <i>folr3</i>) and reduced folate carrier (<i>slc19a1</i>) genes with meningomyelocele

Abstract

This study involved the analyses of selected single nucleotide polymorphisms across the folate receptor genes and the folate carrier gene in a large population sample. It provided evidence that the rare alleles of specific single nucleotide polymorphisms within these genes appear to be statistically significant for association to MM in the patient population that was tested.