<i>PHOX2B</i> Is a Novel and Specific Marker for Minimal Residual Disease Testing in Neuroblastoma

Abstract

PHOX2B is superior to TH and GD2 synthase in specificity and sensitivity for MRD detection of neuroblastoma by using real-time quantitative PCR. We propose to include PHOX2B in additional prospective MRD studies in neuroblastoma alongside TH and other MRD markers.