Publication | Closed Access
A Simple, Reliable, Catalytic Asymmetric Allylation of Ketones
106
Citations
0
References
2002
Year
Cross-coupling ReactionEngineeringQuaternary Stereogenic CentersOrganic ChemistryCatalytic Asymmetric AllylationCatalysisAvailable ReagentsChemistryHomoallylic AlcoholsStereoselective SynthesisAsymmetric CatalysisEnantioselective SynthesisBiomolecular Engineering
Allylation of ketones made easy: commercially available reagents can be used at room temperature to transform ketones into homoallylic alcohols with good to excellent enantioselectivities [Eq. (1)]. This process belongs to a rare class of reactions that catalytically form quaternary stereogenic centers.