Comparison of Long-Term Efficacy of Desmopressin Lyophilisate and Enuretic Alarm for Monosymptomatic Enuresis and Assessment of Predictive Factors for Success: A Randomized Prospective Trial

Abstract

In compliant patients desmopressin lyophilisate and enuretic alarm provided equivalent success at the end of treatment and after extended followup. Alarm therapy had a high rate of early withdrawal from therapy and consequently lower rates of success on intention to treat analyses. Severe enuresis (more than 5 wet nights weekly) is an important predictive factor for cure after first-line treatment.