Kinetic Differentiation between Homo‐ and Alternating AT DNA by Sterically Restricted Phosphonium Dyes

Abstract

Poly has a tracker: By sterically controlling monomer–dimer equilibria, novel dyes can kinetically differentiate between homo-AT and alternating AT–AT polynucleotides. In this way, the width and steric occupation of the DNA minor groove can be finely probed and can be easily assessed by induced CD signals (see figure). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.