Proceedings of the Royal Society of London. Series B, Biological sciences · 1979 · 43 citations · 0 references
Life SciencesEvolutionary BiologyGeneticsEvolutionary TheoryGenome EvolutionMolecular EvolutionEvolutionNatural SelectionOrigins Of LifePolyploid GenomicsResistance EvolutionSelection In PopulationsNatural Selection For ResistanceNatural Selection SignaturesOrigin Of The Genetic CodePolyploid AdaptationPolyploid Evolutionary Genetics
Abstract The Qβ-polymerase-Qβ-RNA system is reviewed and the evolution of resistance to inhibitors is discussed. It is suggested that this system provides a useful model of the evolution of haploid genomes under natural selection. Consequences for theories of the origins of life are discussed.