Design and synthesis of novel spin-labeled camptothecin derivatives as potent cytotoxic agents

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.8K citations

Medicine, Oncology, Pharmacology +10

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata^1,2

Monroe E. Wall, Mansukh C. Wani, Clarence Cook et al. · Journal of the American Chemical Society · 1966 · 2.2K citations

Medicine, Medicinal Chemistry, Pharmacology +8

Highly Efficient One-Pot Synthesis of <i>N</i>-Sulfonylamidines by Cu-Catalyzed Three-Component Coupling of Sulfonyl Azide, Alkyne, and Amine

Imhyuck Bae, Hoon Han, Sukbok Chang · Journal of the American Chemical Society · 2005 · 469 citations

Natural Sciences, Chemistry, Catalysis +13

A kinetic and Mechanistic Study of the Hydrolysis of Camptothecin and Some Analogues

Julianne Fassberg, Valentino J. Stella · Journal of Pharmaceutical Sciences · 1992 · 464 citations

Life Sciences, Biochemistry, Chemistry +12

Camptothecin and Taxol:  Historic Achievements in Natural Products Research

Nicholas H. Oberlies, David J. Kroll · Journal of Natural Products · 2004 · 351 citations

Medicine, Oncology, Pharmacology +16