β‐Type Glycosidic Bond Formation by Palladium‐Catalyzed Decarboxylative Allylation

Abstract

Decarboxylative allylation of glycals: A β-type glycosidic bond has been constructed in high regio- and stereoselectivity by means of a palladium-catalyzed decarboxylative O-glycosylation. Various kinds of glycals with different protecting groups have been examined for this reaction to afford a diverse set of glycosylated products, including phenolic O-glycosides, thiophenolic S-glycoside, aliphatic O-glycosides, and disaccharides with excellent β-selectivity and reasonable to excellent yields.