Concepedia

Publication | Open Access

Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells

DOIFull Paper Access

72

Citations

15

References

2010

Year

Christopher S. Bryant, Sanjeev Kumar, Sreedhar Chamala, Jay P. Shah, Jagannath Pal, Mahdi Haider, Shelly Seward, Aamer Qazi, Robert Morris, Assaad Semaan,
Molecular Cancer

Abstract

SFN induces growth arrest and apoptosis in EOC cells. Inhibition of retinoblastoma (RB) phosphorylation and reduction in levels of free E2F-1 appear to play an important role in EOC growth arrest.

References

YearCitations

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