Attention bias toward threat is associated with exaggerated fear expression and impaired extinction in PTSD

Negar Fani, Erin B. Tone, Justine Phifer, Seth D. Norrholm, Bekh Bradley, Kerry J. Ressler, Asante R. Kamkwalala, Tanja Jovanović

Psychological Medicine · 2011 · 261 citations · 48 references

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Abstract

Our findings indicate that an attentional bias toward threat is associated with abnormalities in 'fear load' in PTSD, providing seminal evidence for an interaction between these two processes. Future research combining these behavioral and psychophysiological techniques with neuroimaging will be useful toward addressing how one process may modulate the other and understanding whether these phenomena are manifestations of dysfunction within a shared neural network. Ultimately, this may serve to inform PTSD treatments specifically designed to correct these atypical processes.

References

48