Therapy-Related Myeloid Neoplasms in Patients With Acute Promyelocytic Leukemia Treated With All-<i>Trans</i>-Retinoic Acid and Anthracycline-Based Chemotherapy

Abstract

t-MN is a relatively infrequent, long-term, and severe complication after first-line treatment for APL with ATRA and anthracycline-based regimens. Therapeutic strategies to reduce the incidence of t-MN are warranted.