The chemistry of drugs part IV, Configurations of antimalarials derived from qinghaosu: Dihydroqingyhaosu, artemether, and artesunic acid

Abstract

Abstract The structures of the antimalarials dihydroqinghaosu (2) , artemether (3) , and artesunic acid (7a) derived from qinghaosu were elaborated by 1 H‐NMR spectroscopy, and supported with X‐ray data obtained for 2 and 3 . Several new derivatives, useful for the chemical characterization of dihydroqinghaosu (2) and artesunic acid (7a) , were prepared.