Induction of endoplasmic reticulum stress and apoptosis by a marine prostanoid in human hepatocellular carcinoma

Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line

David P. Aden, Alice Fogel, Stanley A. Plotkin et al. · Nature · 1979 · 1.3K citations

Hepatology, Oncogenic Agent, Hepatitis +7

CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription.

David Ron, Joel F. Habener · Genes & Development · 1992 · 1.2K citations · Full text

Molecular Biology, Transcriptional Regulation, Transcription Factors C/ebp +16

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2.

K M Kozopas, Tao Yang, Heather L. Buchan et al. · Proceedings of the National Academy of Sciences · 1993 · 965 citations · Full text

Mixed-phenotype Acute Leukemia, Genetics, Tumor Biology +16

Signals from the Stressed Endoplasmic Reticulum Induce C/EBP-Homologous Protein (CHOP/GADD153)

Xiao-Zhong Wang, Beth Lawson, Joseph W. Brewer et al. · Molecular and Cellular Biology · 1996 · 672 citations · Full text

Reductive Stress, Protein Function, Signal Transduction +15

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

Ann–Hwee Lee, Neal N. Iwakoshi, Kenneth C. Anderson et al. · Proceedings of the National Academy of Sciences · 2003 · 595 citations · Full text