Intensified chemotherapy inspired by a pediatric regimen combined with allogeneic transplantation in adult patients with acute lymphoblastic leukemia up to the age of 40

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

Valentino Conter, Claus R. Bartram, Maria Grazia Valsecchi et al. · Blood · 2010 · 786 citations · Full text

Medicine, Hematology, Oncology +11

In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: final results of the International ALL Trial (MRC UKALL XII/ECOG E2993)

Anthony H. Goldstone, Susan Richards, Hillard M. Lazarus et al. · Blood · 2007 · 782 citations · Full text

Medicine, Hematology, Oncology +16

Pediatric-Inspired Therapy in Adults With Philadelphia Chromosome–Negative Acute Lymphoblastic Leukemia: The GRAALL-2003 Study

Françoise Huguet, Thibaut Leguay, Emmanuel Raffoux et al. · Journal of Clinical Oncology · 2009 · 561 citations · Full text

Medicine, Oncology, Pediatrics +15

Outcome of Treatment in Adults With Acute Lymphoblastic Leukemia: Analysis of the LALA-94 Trial

Xavier Thomas, Jean-Michel Boiron, Françoise Huguet et al. · Journal of Clinical Oncology · 2004 · 545 citations · Full text

Medicine, Oncology, Cell Therapy +12

Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia

Monika Brüggemann, Thorsten Raff, Thomas Flohr et al. · Blood · 2005 · 537 citations

Medicine, Hematology, Oncology +16