Minipump Induced Hyperoxaluria and Crystal Deposition in Rats: A Model for Calcium Oxalate Urolithiasis

Abstract

The model of minipump induced hyperoxaluria and crystal deposition in rats reliably induces hyperoxaluria, CaOx crystalluria and CaOx crystal deposition. These characteristics make it an appropriate model for investigations of the effects of OX on renal physiology as well as investigating the efficacy of new therapeutics.