Physics of Fluids · 2008 · 166 citations · 26 references
Natural SciencesBiophysicsFluid DynamicsMembrane TraffickingTransport PhenomenaBiofluid MechanicsExternal FlowMembrane TransportViscous FlowLateral MigrationMicrochannel HydrodynamicsMigration Of FluidsMigration VelocityPoiseuille FlowViscosity
Cross-streamline noninertial migration of a vesicle in a bounded Poiseuille flow is investigated experimentally and numerically. The combined effects of the walls and of the curvature of the velocity profile induce a movement toward the center of the channel. A migration law (as a function of relevant structural and flow parameters) is proposed that is consistent with experimental and numerical results. This similarity law markedly differs from its analog in unbounded geometry. The dependency on the reduced volume ν and viscosity ratio λ is also discussed. In particular, the migration velocity becomes nonmonotonous as a function of ν beyond a certain λ.
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Biomechanics. Mechanical Properties of Living Tissues
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