Highly active antibacterial ferrocenoylated or ruthenocenoylated Arg-Trp peptides can be discovered by an<scp>l</scp>-to-<scp>d</scp>substitution scan

Bauke Albada, Pascal Prochnow, Sandra Bobersky, Julia E. Bandow, Nils Metzler‐Nolte

Chemical Science · 2014 · 47 citations · 25 references

Concepts

Abstract

By taking a systematic approach several short organometallic AMP conjugates were discovered which have very low hemolytic activity but virtually the same antimicrobial activity against MRSA as that of vancomycin.

References

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