Control Banding Approaches for Nanomaterials

Abstract

Control banding (CB) has been developed as a pragmatic tool to manage the risk resulting from exposure to a wide variety of potentially hazardous substances in the absence of firm toxicological and exposure information. Currently, the CB approach is applied for emerging risks such as nanoparticles, by the development of various CB-based tools. Six of these are compared. Despite their similarity, i.e. combining hazard and exposure into control or risk bands, the structure, the applicability domains, and the assignment of the hazard and exposure bands, show differences that may affect the consistency of the resulting outcome amongst the various CB tools. The value of the currently available CB tools for nanomaterials can be enhanced by transparently elucidating these differences for user consideration during the selection of a tool for a specific scenario of application.