Concepedia

Higher glutathione transferase GSTM1 0/0 genotype frequency in young thyroid carcinoma patients

Emel Canbay, Hatice Sebila Dökmetaş, Ercan Canbay, Metin Şen, Fevzi Bardakçi

Current Medical Research and Opinion · 2003 · 14 citations · 12 references

DOI

Abstract

GSTM1 deleted genotype may be a useful genetic biomarker for thyroid carcinoma susceptibility in young subjects. The absence of this enzyme seems to have a role in the development of thyroid carcinoma; however, the mechanism still needs further study.

References

12

Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk.

Jürgen Brockmöller, Ingolf Cascorbi, Reinhold Kerb et al. · PubMed · 1996 · 332 citations

, , +16

Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) geneticpolymorphism and susceptibility to gastric and colorectaladenocarcinoma

Takahiko Katoh, Naoki Nagata, Yusuke Kuroda et al. · Carcinogenesis · 1996 · 252 citations

The <i>GSTM1</i> null genotype as a potential risk modifier for squamous cell carcinoma of the lung

Ari Hirvonen, Kirsti Husgafvel-Pursiainen, Sisko Anttila et al. · Carcinogenesis · 1993 · 238 citations

Ethnic distribution of the glutathione transferase Mu 1-1 (<i>GSTM1</i>) null genotype in 1473 individuals and application to bladder cancer susceptibifity

Henry J. Lin, Chun-Ya Han, David A. Bernstein et al. · Carcinogenesis · 1994 · 171 citations

Human glutathione S-transferase μ (GSTμ) deficiency as a marker for the susceptibility to bladder and larynx cancer among smokers

Amàlia Lafuente, Pablo Carretero, Jesús Pérez Villa et al. · Cancer Letters · 1993 · 160 citations

, , +7