Concepedia

FTY720 and Cyclosporine: Evaluation for a Pharmacokinetic Interaction

John M. Kovarik, Robert Schmouder, Denise Barilla, Monika Büche, Marisel Rouilly, Stephane Berthier, Yibin Wang, Claudia Van Saders, Thomas U. Mayer, Alice B. Gottlieb

Annals of Pharmacotherapy · 2004 · 15 citations · 6 references

DOI

Abstract

The pharmacokinetics of single-dose FTY720 and steady-state cyclosporine were not altered during coadministration.

References

6

FTY720 Immunosuppression Impairs Effector T Cell Peripheral Homing Without Affecting Induction, Expansion, and Memory

Daniel D. Pinschewer, Adrian F. Ochsenbein, Bernhard Odermatt et al. · The Journal of Immunology · 2000 · 362 citations

First Human Trial of FTY720, a Novel Immunomodulator, in Stable Renal Transplant Patients

Klemens Budde, Robert Schmouder, R. Brunkhorst et al. · Journal of the American Society of Nephrology · 2002 · 273 citations

Pharmacodynamics, pharmacokinetics, and safety of multiple doses of FTY720 in stable renal transplant patients: a multicenter, randomized, placebo-controlled, phase I study

Barry D. Kahan, Janet L. Karlix, Ronald M. Ferguson et al. · Transplantation · 2003 · 126 citations

Single‐dose FTY720 pharmacokinetics, food effect, and pharmacological responses in healthy subjects

John M. Kovarik, Robert Schmouder, Denise Barilla et al. · British Journal of Clinical Pharmacology · 2004 · 81 citations · Full text

Effects of sphingosine 1-phosphate on pacemaker activity in rabbit sino-atrial node cells

Jia Guo, Karen L. MacDonell, Wayne R. Giles · Pflügers Archiv - European Journal of Physiology · 1999 · 74 citations

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