A New Nickel‐Catalyzed Cross‐Coupling Reaction between sp³ Carbon Centers

Abstract

Polyfunctional dialkylzinc compounds and primary alkyl iodides bearing a remote double bond undergo nickel-catalyzed cross-coupling even at −35 °C within a few hours, as shown in the example below. The resulting polyfunctional products are formed in good yield. NMP = N-methyl-2-pyrrolidinone, acac = acetylacetonate, Piv = pivaloyl.