Concepedia

Reactive Oxygen Species Mediate TNFR1 Increase after TRPV1 Activation in Mouse DRG Neurons

Fei Ma, Liping Zhang, Karin N. Westlund

Molecular Pain · 2009 · 88 citations · 40 references

DOIFull text

Open access

Abstract

TRPV1 activation increases TNFR1 in cultured mouse DRG neurons through a ROS signaling pathway, a novel sensitization mechanism in DRG neurons.

References

40

Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

Michael J. Caterina, Andreas Leffler, Annika B. Malmberg et al. · Science · 2000 · 3.5K citations

Requirement for Generation of H <sub>2</sub> O <sub>2</sub> for Platelet-Derived Growth Factor Signal Transduction

Maitrayee Sundaresan, Zu-Xi Yu, Victor J. Ferrans et al. · Science · 1995 · 2.5K citations

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

John B. Davis, Julie Gray, Martin J. Gunthorpe et al. · Nature · 2000 · 1.7K citations

, , +7

Mitogenic Signaling Mediated by Oxidants in Ras-Transformed Fibroblasts

Kaikobad Irani, Yong Xia, Jay L. Zweíer et al. · Science · 1997 · 1.6K citations

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

Huai-hu Chuang, Elizabeth D. Prescott, Haeyoung Kong et al. · Nature · 2001 · 1.2K citations

, , +10