Montmorillonite K10 Clay Catalyzed Mild, Clean, Solvent Free One-pot Protection-Isomerisation of the Baylis–Hillman Adducts with Alcohols

Abstract

Abstract The montmorillonite K10 clay catalyzed mild, clean, and solvent free one-pot reactions of the Baylis–Hillman adducts with a number of alcohols undergo secondary alcohol protection followed by a facile 1,3-sigmatropic shift isomerised products in excellent yield. The isomerised products with propargyl alcohol are highly functionalized and useful for lignan natural product synthesis.