Concepedia

Organocatalytic asymmetric aza-Nazarov cyclization of an azirine

Naoyuki Shimada, B.O. Ashburn, A. K. Basak, William F. Bow, David A. Vicic, Marcus A. Tius

Chemical Communications · 2010 · 76 citations · 37 references

DOI

Concepts

Abstract

An unusual organocatalytic asymmetric cyclization of a ketoazirine that is accompanied by a kinetic resolution leads to 4-hydroxy-3-oxo-1,2,3,6-tetrahydropyridine-2-carboxylates in >99/1 er.

References

37

The Nazarov cyclization in organic synthesis. Recent advances

Alison J. Frontier, Christina G. Collison · Tetrahedron · 2005 · 466 citations

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Recent developments in the Nazarov process

Hélène Pellissier · Tetrahedron · 2005 · 411 citations

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Some New Nazarov Chemistry

Marcus A. Tius · European Journal of Organic Chemistry · 2005 · 355 citations

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Interrupting the Nazarov reaction: domino and cascade processes utilizing cyclopentenyl cations

Tina N. Grant, Curtis J. Rieder, F. G. West · Chemical Communications · 2009 · 257 citations

, , +13

Enantioselective Claisen Rearrangements with a Hydrogen-Bond Donor Catalyst

Christopher Uyeda, Eric N. Jacobsen · Journal of the American Chemical Society · 2008 · 253 citations · Full text

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