Concepedia

Clozapine-Induced Agranulocytosis Treated with Granulocyte Macrophage Colony Stimulating Factor

Ran Oren, Elaine Granat, Shlomo Shtrussberg, Yaacov Matzner

The British Journal of Psychiatry · 1993 · 19 citations · 10 references

DOI

Concepts

Abstract

Clozapine-induced agranulocytosis is usually reversible after discontinuation of the drug. A patient who developed agranulocytosis after termination of clozapine therapy responded to treatment with granulocyte macrophage colony stimulating factor.

References

10

Clozapine for the Treatment-Resistant Schizophrenic

John M. Kane · Archives of General Psychiatry · 1988 · 4.1K citations

, , +16

Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival.

Angel F. López, Dominic J. Williamson, Jennifer R. Gamble et al. · Journal of Clinical Investigation · 1986 · 717 citations · Full text

, , +17

Effects of Recombinant Human Granulocyte Colony-Stimulating Factor on Neutropenia in Patients with Congenital Agranulocytosis

Mary Ann Bonilla, Mary Ruggeiro, Nancy A. Kernan et al. · New England Journal of Medicine · 1989 · 497 citations

, , +16

Biologic properties in vitro of a recombinant human granulocyte- macrophage colony-stimulating factor

D Metcalf, C. Glenn Begley, GR Johnson et al. · Blood · 1986 · 455 citations

, , +8

Human Recombinant Granulocyte-Macrophage Colony-Stimulating Factor: A Multilineage Hematopoietin

Colin A. Sieff, Stephen G. Emerson, Robert E. Donahue et al. · Science · 1985 · 357 citations

, , +14