Randomized, Placebo-Controlled, Phase III Study of Oxaliplatin, Fluorouracil, and Leucovorin With or Without PTK787/ZK 222584 in Patients With Previously Treated Metastatic Colorectal Adenocarcinoma - Concepedia

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Randomized, Placebo-Controlled, Phase III Study of Oxaliplatin, Fluorouracil, and Leucovorin With or Without PTK787/ZK 222584 in Patients With Previously Treated Metastatic Colorectal Adenocarcinoma

161

Citations

18

References

2011

Year

Eric Van Cutsem, Emilio Bajetta, Juan W. Valle, Claus-Henning Köhne, J. Randolph Hecht, Malcolm J. Moore, Colin Germond, William J. Berg, Bee-Lian Chen, T. Jalava,

Journal of Clinical Oncology

Abstract

PTK/ZK in combination with FOLFOX4 did not improve OS of patients with pretreated mCRC but did improve PFS. The effect of PTK/ZK was more pronounced in patients with high LDH at baseline.

References

	Year	Citations

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