Tubuloreticular structures within labial salivary glands in sjögren's syndrome

Abstract

Abstract Tubuloreticular structures were found in endothelial cells of biopsies from labial salivary glands of 6 of 20 patients with Sjögren's syndrome, and were absent in 11 control patients. Patients with these structures had evidence of severe disease as manifested by xerostomia, lymphoid infiltrates in the salivary glands, hypergammaglobulinemia, and auto‐antibodies. The nature of these inclusions remains controversial.