Gold‐ or Platinum‐Catalyzed Tandem Cycloisomerization/Prins‐Type Cyclization Reactions

Abstract

Straightforward and efficient: Functionalized eight-membered carbocycles are easily obtained from simple allyl-substituted 5-hexyn-1-ol derivatives by a catalytic tandem sequence involving a 6-exo cycloisomerization followed by a Prins-type cyclization (see scheme).