Concepedia

Publication | Open Access

PintlincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2

DOIFull Paper Access

266

Citations

29

References

2013

Year

Oskar Marín-Béjar, Francesco P. Marchese, Alejandro Athie, Yolanda Sánchez, Jovanna González, Víctor Segura, Lulu Huang, Isabel Moreno, Alfons Navarro, Mariano Monzó,
Genome biology

Abstract

Our results reveal a p53 autoregulatory negative mechanism where a lincRNA connects p53 activation with epigenetic silencing by PRC2. Additionally, we show analogies and differences between the murine and human orthologs, identifying a novel tumor suppressor candidate lincRNA.

References

YearCitations

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