Small · 2013 · 22 citations · 0 references
EngineeringBioengineeringBiomedical EngineeringBiosensorsDrug DeliveryNanobiotechnologyBiosensors For Immune DetectionNanomaterial-based BiosensorsNanomedicineNanoparticle Delivery SystemsQuantum DotsQuantum Dots In BiologyEmulsificationImmunoassaysMultiplexed ImmunoassaysNanoparticle-based ImmunoassaysQuantum Dot BiosensorsQuantum Dot Drug DeliveryQuantum Dot ImagingSemiconductor Quantum Dots
A detection platform combining NIR emitting CdSeTe/CdS/ZnS quantum dot (QD)-encoded microbeads and flow cytometry with a 488 nm laser is described on page 3327 by W. Li, K. Sun, X. Chen, and co-workers. This platform is used to conduct a 2-plex hybridization assay for hepatitis B surface antigen, hepatitis Be antigen and a 3-plex hybridization assay for hepatitis B surface antibody, hepatitis Be antibody and hepatitis B core antibody, which suggests the promising application of NIR QDencoded microbeads for multiplexed immunoassays.