Non‐resectable congenital tumors with the <i>ETV6</i>–<i>NTRK3</i> gene fusion are highly responsive to chemotherapy

Emma McCahon, Poul H. Sorensen, Jeffrey Davis, Paul Rogers, Kirk R. Schultz

Medical and Pediatric Oncology · 2003 · 71 citations · 16 references

Abstract

Our findings suggest that the ETV6-NTRK3 gene fusion may underlie the distinctive biological properties of these tumors and may also indicate tumor chemosensitivity. In this group of patients pre-operative chemotherapy may abrogate the need for morbid surgical procedures.

References

16