Concepedia

ROCK inhibitor improves survival of cryopreserved serum/feeder-free single human embryonic stem cells

Xiaoyan Li, Roman Krawetz, S. Liu, Derrick E. Rancourt

Human Reproduction · 2008 · 163 citations · 28 references

Abstract

The method described here allows for cryopreservation of single hES cells in serum-free and feeder-free conditions and therefore we believe this method will be ideal for current and future hES cell applications that are targeted towards a therapeutic end-point.

References

28

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James A. Thomson, Joseph Itskovitz‐Eldor, Sander S. Shapiro et al. · Science · 1998 · 15.8K citations

Telomerase Activity, Adult Stem Cell, Biomedical Engineering +16

Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

Benjamin Reubinoff, Martín F. Pera, Chui‐Yee Fong et al. · Nature Biotechnology · 2000 · 2.7K citations

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +13

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

Kiichi Watanabe, Morio Ueno, Daisuke KAMIYA et al. · Nature Biotechnology · 2007 · 2.1K citations

Developmental Biology, Medicine, Adult Stem Cell +8

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Tenneille E. Ludwig, Mark E. Levenstein, Jeffrey M. Jones et al. · Nature Biotechnology · 2006 · 1.1K citations

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +10

Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase

Mutsuki Amano, Kazuyasu Chihara, Kazushi Kimura et al. · Science · 1997 · 1.1K citations

Engineering, Cell Adhesion, Cytoskeleton +20