Computational design of synthetic gene circuits with composable parts

A synthetic oscillatory network of transcriptional regulators

Michael B. Elowitz, Stanislas Leibler · Nature · 2000 · 4.7K citations

Transcriptional Regulation, Signal Transduction, Engineering +9

Construction of a genetic toggle switch in Escherichia coli

Timothy S. Gardner, Charles R. Cantor, James J. Collins · Nature · 2000 · 4.3K citations

Engineering, Genetic Engineering, Molecular Biology +7

The systems biology markup language (SBML): a medium forrepresentation and exchange of biochemical network models

Michael Hucka, Andrew Finney, Herbert M. Sauro et al. · Bioinformatics · 2003 · 3.1K citations · Full text

COPASI—a COmplex PAthway SImulator

Stefan Hoops, Sven Sahle, Ralph Gauges et al. · Bioinformatics · 2006 · 2.7K citations · Full text

Synthetic biology: new engineering rules for an emerging discipline

Ernesto Andrianantoandro, Subhayu Basu, David Karig et al. · Molecular Systems Biology · 2006 · 1.1K citations · Full text

Engineering, Genetic Circuits, Biotechnology +4