Asymmetric Synthesis Utilizing Circularly Polarized Light Mediated by the Photoequilibrium of Chiral Olefins in Conjunction with Asymmetric Autocatalysis

Abstract

The light touch: Asymmetric photoequilibrium and autocatalysis act as sources of homochirality in a highly enantioselective preparation of chiral alcohols (see scheme). This process is initiated by left- and right-circularly polarized light (CPL) and exploits the resulting photoequilibrium between chiral olefin substrates to yield 2-alkynyl-5-pyrimidyl alkanols. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2004/z54162_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.