Concepedia

Cyclooxygenase-2 Expression

Labile Togba Soumaoro, Hiroyuki Uetake, Tetsuro Higuchi, Yoko Takagi, Masayuki Enomoto, Kenichi Sugihara

Clinical Cancer Research · 2004 · 253 citations · 46 references

DOI

Abstract

Elevated Cox-2 expression, but not that of Cox-1, was significantly associated with reduced survival and recognized as an independent prognostic factor in our cohort of colorectal cancer patients.

References

46

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

Charles E. Eberhart, R J Coffey, Radhika Aramandla et al. · Gastroenterology · 1994 · 2.5K citations · Full text

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Masanobu Oshima, Joseph Dinchuk, Stacia Kargman et al. · Cell · 1996 · 2.4K citations · Full text

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Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

Masahiko Tsujii, Raymond N. DuBois · Cell · 1995 · 2.3K citations · Full text

, , +13

Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells

Masahiko Tsujii, Sunao Kawano, Shingo Tsuji et al. · Cell · 1998 · 2.3K citations · Full text

, , +4

Aspirin Use and Reduced Risk of Fatal Colon Cancer

Michael J. Thun, Mohan M. Namboodiri, Clark W. Heath · New England Journal of Medicine · 1991 · 1.7K citations · Full text

, , +15