Infection Control and Hospital Epidemiology · 2002 · 115 citations · 31 references
Veterinary MedicineInfectious DiseasesInternal MedicineImmunizationInfectious Disease EpidemiologyOutbreak InvestigationHealthcare-associated InfectionsNosocomial Infection EpidemiologyNosocomial InfectionsOutbreak ControlOutbreak ManagementRespiratory Infectious DiseasesCohort Study InvestigationHealth Care EconomicsHealthcare-associated OutbreaksHospital Infection Outbreak InvestigationHospital Outbreak InvestigationIndex Case InvestigationNosocomial Outbreak DynamicsViral Outbreak Investigation
OBJECTIVE: To describe a nosocomial influenza A outbreak, how it was managed, what impact it had on subsequent delivery of health care, and the additional charges attributable to it DESIGN: Prospective cohort study and microbiological investigation. SETTING: One internal medicine unit in an acute care, university-affiliated hospital. PARTICIPANTS: Twenty-three patients and 22 staff members from February 28 to March 6, 1999. RESULTS: Attack rates were 41% (9 of 22) among patients and 23% (5 of 22) among staff members, with 3 of 14 cases being classified as "certain." The influenza virus isolates were typed as A/SYDNEY/5/97 (H3N2). The index case was a patient who shared a room with the first nosocomial case. Vaccination rates for influenza virus were 43% (10 of 23) among patients and 36% (8 of 22) among staff members. The outbreak resulted in staff members' taking 14 person-days of sick leave. Furthermore, 8 scheduled admissions were postponed and all emergency admissions were suspended for 11 days. Hospital charges attributable to the influenza outbreak totaled $34,179 and the average extra charge per infected patient was $3,798. CONCLUSIONS: Nosocomial influenza outbreaks increase charges and alter the quality of care delivered in acute care settings. Strategies for their prevention need to be evaluated in acute care settings.
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Effectiveness of Influenza Vaccine in Health Care Professionals
James A. Wilde, Julia A. McMillan, Janet R. Serwint et al. · JAMA · 1999 · 599 citations
Inhaled Zanamivir for the Prevention of Influenza in Families
Frederick G. Hayden, Larisa V. Gubareva, Arnold S. Monto et al. · New England Journal of Medicine · 2000 · 375 citations · Full text
Carolyn B. Bridges, Jacqueline M. Katz, Paul K.S. Chan et al. · The Journal of Infectious Diseases · 2000 · 238 citations
Veterinary Medicine, Infectious Diseases, Emerging Infectious Diseases +12