Concepedia

Publication | Open Access

Attenuation of Nitrate Tolerance and Oxidative Stress by an Angiotensin II Receptor Blocker in Patients With Coronary Spastic Angina

DOIFull Paper Access

65

Citations

27

References

2003

Year

Nobutaka Hirai, Hiroaki Kawano, Hirofumi Yasue, Hideki Shimomura, Shinzo Miyamoto, Hirofumi Soejima, Ichiro Kajiwara, Tomohiro Sakamoto, Michihiro Yoshimura, Hajime Nakamura,
Circulation

Abstract

An ARB suppressed the development of nitrate tolerance during transdermal nitroglycerin therapy. These results suggest that increased oxidative stress induced by activation of angiotensin II may play an important role in the development of nitrate tolerance.

References

YearCitations

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