<i>N</i>'-<i>tert</i>-Butyl-<i>N</i>'-aroyl-<i>N</i>-(alkoxycarbonylmethyl)-<i>N</i>-aroylhydrazines, a novel nonsteroidal ecdysone agonist: syntheses, insecticidal activity, conformational, and crystal structure analysis

Abstract

Seventeen N'-tert-butyl-N'-aroyl-N-(alkoxycarbonylmethyl)-N-aroylhydrazines were synthesized, and their insecticidal activities against armyworm (Leucania separata (Walker)) were tested. The conformation and structure of compound 1b was studied by 1 H NMR spectroscopy and X-ray crystallography. The crystal structure belongs to the orthorhombic system and the N—N bond adopts a gauche conformation, which was assumed to be the active conformation, with a dihedral angle of 69.9°.Key words: N'-tert-butyl-N'-aroyl-N-(alkoxycarbonylmethyl)-N-aroylhydrazine, syntheses, insecticidal activity, conformation, crystal structure.