Chemical Communications · 2013 · 270 citations · 19 references
PharmacyPharmaceuticsPharmacologyDrug DeliveryNanomaterialsNanoparticle Drug DeliveryDrug Delivery SystemsNanomaterials For Drug DeliveryNanomedicineNanoparticle Delivery SystemsNanoparticle DesignNanoparticle FormulationsDoxorubicin-based TherapyDrug Delivery NanocarriersDrug Loading AnalysisMacromolecular Drug LoadingNanoparticle-based ChemotherapyPh-responsive Polymeric NanoparticlesPh-sensitive NanoparticlesPolymeric Nanocarriers
The polyacrylic acid@zeolitic imidazolate framework-8 (PAA@ZIF-8) nanoparticles (NPs) were first fabricated using a facile and simple route. It is worthwhile noting that the as-fabricated PAA@ZIF-8 NPs possessed ultrahigh doxorubicin (DOX) loading capability (1.9 g DOX g(-1) NPs), which were employed as pH-dependent drug delivery vehicles.
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Zeolitic imidazolate framework-8 as efficient pH-sensitive drug delivery vehicle
Chunyi Sun, Chao Qin, Xinlong Wang et al. · Dalton Transactions · 2012 · 705 citations