Nasopharyngeal Carriage of Penicillin-resistant<i>Streptococcus pneumoniae</i>in Children With Sickle Cell Disease

Abstract

There is a high prevalence of NP carriage of PRSP in children with SCD in the Mid-South, which raises concerns regarding the continued effectiveness of penicillin prophylaxis in these children. Further studies on the antimicrobial susceptibilities of resistant organisms and the relationship between NP carriage of SP and invasive disease are needed before developing new recommendations for prophylaxis and treatment.