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Catalytic enantioselective arylation of aldehydes: boronic acids as a suitable source of transferable aryl groups
73
Citations
26
References
2005
Year
Chemical EngineeringCross-coupling ReactionEngineeringTransferable Aryl GroupsCatalytic Enantioselective ArylationBoronic AcidsOrganic ChemistryCatalysisStereoselective SynthesisChemistryChiral Amino AlcoholAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular Engineering
The catalytic enantioselective arylation of several aldehydes using boronic acids as the source of transferable aryl groups is described; the reaction is found to proceed in excellent yields and high enantioselectivities (up to 97% ee) in the presence of a chiral amino alcohol.
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