Serum Gastrin and Mucosal Somatostatin in<i>Helicobacter</i>pylori-Associated Gastritis

Abstract

These results suggest that hypergastrinemia in H. pylori gastritis is not caused by antral gastritis and antral somatostatin deficiency alone but that corpus inflammation plays a key role in the origin of hypergastrinemia. Furthermore, in patients with pangastritis a corpus mucosal somatostatin deficiency was found.