The role of costimulatory molecules (B7‐1 and B7‐2) on allergen‐stimulated B cells in cedar pollinosis subjects

Abstract

These results indicated that TH2 response was predominant in pollinosis subjects, and that CD19+ cells of pollinosis subjects expressed higher levels of B7-2 than those of control subjects after in vitro stimulation. In pollinosis subjects, B7-2 rather than B7-1 may be the costimulatory molecule involved in allergen-induced activation of PBMCs.