Diverse phenotypes and transfusion requirements due to interaction of β-thalassemias with triplicated α-globin genes

Triplicated alpha-globin loci in humans.

M. Goossens, A M Dozy, Stephen H. Embury et al. · Proceedings of the National Academy of Sciences · 1980 · 241 citations · Full text

Biology, Immunohematology, Allelic Variant +15

The triplicated α‐globin gene locus in β‐thalassaemia heterozygotes: clinical, haematological, biosynthetic and molecular studies

Joanne Traeger‐Synodinos, Emmanuel Kanavakis, Christina Vrettou et al. · British Journal of Haematology · 1996 · 93 citations

Immunohematology, Clinical Symptoms, β‐Thalassaemia Heterozygotes +15

Different hematological phenotypes caused by the interaction of triplicated α-globin genes and heterozygous β-thalassemia

Clara Camaschella, Antonios Kattamis, D. Petroni et al. · American Journal of Hematology · 1997 · 58 citations

Frequency of α-Globin Gene Triplications and Their Interaction with β-Thalassemia Mutations

Piero C. Giordano, Margaretha Bakker-Verwij, Cornelis L. Harteveld · Hemoglobin · 2009 · 51 citations

A novel molecular basis for β thalassemia intermedia poses new questions about its pathophysiology

Anuja Premawardhena, Christopher A. Fisher, Nancy F. Olivieri et al. · Blood · 2005 · 46 citations · Full text