British Journal of Ophthalmology · 1988 · 143 citations · 20 references
MedicineOphthalmologyPharmacologyClinical PharmacologyOcular DiseaseOcular PharmacologyCataract EpidemiologyCataract ManagementMedication Effects On VisionCase-control Study DesignCataract Risk Factor AssessmentOphthalmic Drug SafetySpironolactone TherapyTobacco Smoking
A case-control study of cataract in Oxfordshire explored the risks and benefits associated with a variety of drugs. Steroids including the diuretic spironolactone, nifedipine, heavy smoking, and beer drinking were associated with a raised risk. On the other hand aspirin-like analgesics (paracetamol, ibuprofen, aspirin, etc. appeared to protect against cataract. Cyclopenthiazide appeared to provide a similar protection.
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2015 · 270 citations
James Reid, A.I. Macdougall, M.M. Andrews · BMJ · 1957 · 184 citations · Full text
DIABETIC RETINOPATHY AND RHEUMATOID ARTHRITIS
ElinorD.U. Powell, RichardA. Field · The Lancet · 1964 · 151 citations
DO ASPIRIN-LIKE ANALGESICS PROTECT AGAINST CATARACT?
RuthVan Heyningen, JohnJ. Harding · The Lancet · 1986 · 103 citations
M. Rufus Crompton, Ken C. Rixon, John J. Harding · Experimental Eye Research · 1985 · 103 citations